Prim-O-glucosylcimifugin enhances the antitumour effect of PD-1 inhibition by targeting myeloid-derived suppressor cells

BACKGROUND: Myeloid-derived suppressor cells (MDSCs) are immunosuppressive cells that play an important role in immune evasion, PD-1/PD-L1 inhibitor tolerance and tumour progression. Therefore, MDSCs are potential targets for cancer immunotherapy. In this study, we screened an effective polymorphonu...

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Publicat a:J Immunother Cancer
Autors principals: Gao, Wanfeng, Zhang, Xiaoyun, Yang, Wendong, Dou, Daolei, Zhang, Heng, Tang, Yuanhao, Zhong, Weilong, Meng, Jing, Bai, Yun, Liu, Yanrong, Yang, Lan, Chen, Shuang, Liu, Huijuan, Yang, Cheng, Sun, Tao
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714432/
https://ncbi.nlm.nih.gov/pubmed/31462297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0676-z
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