Deletion at 2q14.3 is associated with worse response to TNF-α blockers in patients with rheumatoid arthritis

BACKGROUND: Structural variations such as copy number variations (CNVs) have a functional impact on various human traits. This study profiled genome-wide CNVs in Korean patients with rheumatoid arthritis (RA) to investigate the efficacy of treatment with TNF-α blockers. METHODS: A total of 357 Korea...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Gu, Ki-Nam, Bang, So-Young, Lee, Hye-Soon, Park, Youngho, Kang, Ju-Yeon, Kim, Ji-Soong, Nam, Bora, Yoo, Hyun-Seung, Shin, Jung-Min, Lee, Yeon-Kyung, Lee, Tae-Han, Chun, Sehwan, Cho, Soo-Kyung, Choi, Chan-Bum, Sung, Yoon-Kyoung, Kim, Tae-Hwan, Jun, Jae-Bum, Yoo, Dae Hyun, Kim, Kwangwoo, Bae, Sang-Cheol
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714408/
https://ncbi.nlm.nih.gov/pubmed/31462329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-019-1983-y
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