Exosomes derived from microRNA-138-5p-overexpressing bone marrow-derived mesenchymal stem cells confer neuroprotection to astrocytes following ischemic stroke via inhibition of LCN2

BACKGROUND: MicroRNAs (miRNAs) are implicated in the progression of ischemic stroke (IS) and bone marrow-derived mesenchymal stem cells (BMSCs)-derived exosomes play a role in IS therapy. Herein we hypothesized that the BMSCs-derived exosomes containing overexpressed miR-138-5p could protect the ast...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Eng
Main Authors: Deng, Yiming, Chen, Duanduan, Gao, Feng, Lv, Hong, Zhang, Guojun, Sun, Xuan, Liu, Lian, Mo, Dapeng, Ma, Ning, Song, Ligang, Huo, Xiaochuan, Yan, Tianyi, Zhang, Jingbo, Miao, Zhongrong
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714399/
https://ncbi.nlm.nih.gov/pubmed/31485266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-019-0193-0
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki