Application of Factorial and Doehlert Designs for the Optimization of the Simultaneous Separation and Determination of Antimigraine Drugs in Pharmaceutical Formulations by RP-HPLC-UV

A sensitive, precise, accurate, and specific isocratic reversed-phase high-performance liquid chromatographic (RP-HPLC) method for the simultaneous separation and determination of zolmitriptan, naratriptan, dihydroergotamine, ketotifen, and pizotifen in pharmaceutical formulations has been developed...

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Detalhes bibliográficos
Publicado no:Int J Anal Chem
Main Authors: Jebali, Sami, Belgacem, Chaouki, Louhaichi, Mohamed Radhouen, Bahri, Senda, Latrous El Atarche, Latifa
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714324/
https://ncbi.nlm.nih.gov/pubmed/31511775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/9685750
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