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Bioactivation of the tobacco carcinogens 4-aminobiphenyl (4-ABP) and 2-amino-9H-pyrido[2,3-b]indole (AαC) in human bladder RT4 cells

Occupational and tobacco exposure to aromatic amines (AAs) including 4-aminobiphenyl (4-ABP) and 2-naphthylamine (2-NA) are associated with bladder cancer (BC) risk. Several epidemiological studies have also reported a possible role for structurally related heterocyclic aromatic amines (HAAs) formed...

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Detalhes bibliográficos
Publicado no:Arch Toxicol
Main Authors: Bellamri, Medjda, Yao, Lihua, Bonala, Radha, Johnson, Francis, Von Weymarn, Linda B., Turesky, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714057/
https://ncbi.nlm.nih.gov/pubmed/31203411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-019-02486-7
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