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IL-4(−/−) mice with lethal Mesocestoides corti infections – reduced Th2 cytokines and alternatively activated macrophages

Protection against Mesocestoides corti, a cestode that invades vital organs, is dependent on the production of IL-4, as IL-4(−/−) mice were found to have higher parasite burdens when compared with wild-type mice. The goal of this study was to investigate the role of IL-4 in immunity to M. corti, foc...

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Detalhes bibliográficos
Publicado no:Parasite Immunol
Main Authors: O’CONNELL, A. E., KEREPESI, L. A., VANDERGRIFT, G. L., HERBERT, D. R., VAN WINKLE, T. J., HOOPER, D. C., PEARCE, E. J., ABRAHAM, D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714042/
https://ncbi.nlm.nih.gov/pubmed/19891612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-3024.2009.01151.x
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