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Blocking Formation of the Stable HIV Reservoir: A New Perspective for HIV-1 Cure

Recent studies demonstrate that the stable HIV-1 reservoir in resting CD4(+) T cells is mostly formed from viruses circulating when combination antiretroviral therapy (ART) is initiated. Here we explore the immunological basis for these observations. Untreated HIV-1 infection is characterized by a p...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Goonetilleke, Nilu, Clutton, Genevieve, Swanstrom, Ron, Joseph, Sarah B.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714000/
https://ncbi.nlm.nih.gov/pubmed/31507594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01966
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