Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins

MIB1 belongs to the RING domain containing family of E3 ubiquitin ligases. In vertebrates, MIB1 plays an essential role in activation of Notch signaling during development, through the ubiquitination and endocytosis of Notch ligands. More recently, Notch independent functions for MIB1 have been desc...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Dho, Sascha E., Silva-Gagliardi, Nancy, Morgese, Fabio, Coyaud, Etienne, Lamoureux, Emily, Berry, Donna M., Raught, Brian, McGlade, C. Jane
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6713736/
https://ncbi.nlm.nih.gov/pubmed/31462741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48902-x
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