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Bta-miR-10b Secreted by Bovine Embryos Negatively Impacts Preimplantation Embryo Quality

In a previous study, we found miR-10b to be more abundant in a conditioned culture medium of degenerate embryos compared to that of blastocysts. Here, we show that miR-10b mimics added to the culture medium can be taken up by embryos. This uptake results in an increase in embryonic cell apoptosis an...

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Pubblicato in:Front Genet
Autori principali: Lin, Xiaoyuan, Pavani, Krishna Chaitanya, Smits, Katrien, Deforce, Dieter, Heindryckx, Björn, Van Soom, Ann, Peelman, Luc
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6713719/
https://ncbi.nlm.nih.gov/pubmed/31507632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00757
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