The adhesion-GPCR BAI1 shapes dendritic arbors via Bcr-mediated RhoA activation causing late growth arrest

Dendritic arbor architecture profoundly impacts neuronal connectivity and function, and aberrant dendritic morphology characterizes neuropsychiatric disorders. Here, we identify the adhesion-GPCR BAI1 as an important regulator of dendritic arborization. BAI1 loss from mouse or rat hippocampal neuron...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Duman, Joseph G, Mulherkar, Shalaka, Tu, Yen-Kuei, Erikson, Kelly C, Tzeng, Christopher P, Mavratsas, Vasilis C, Ho, Tammy Szu-Yu, Tolias, Kimberley F
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2019
Assuntos:
Developmental Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6713510/
https://ncbi.nlm.nih.gov/pubmed/31461398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.47566
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