Combinatorial morphogenetic and mechanical cues to mimic bone development for defect repair

Endochondral ossification during long bone development and natural fracture healing initiates by mesenchymal cell condensation, directed by local morphogen signals and mechanical cues. Here, we aimed to mimic development for regeneration of large bone defects. We hypothesized that engineered human m...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Herberg, S., McDermott, A. M., Dang, P. N., Alt, D. S., Tang, R., Dawahare, J. H., Varghai, D., Shin, J.-Y., McMillan, A., Dikina, A. D., He, F., Lee, Y. B., Cheng, Y., Umemori, K., Wong, P. C., Park, H., Boerckel, J. D., Alsberg, E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6713501/
https://ncbi.nlm.nih.gov/pubmed/31489377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax2476
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