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Combinatorial morphogenetic and mechanical cues to mimic bone development for defect repair
Endochondral ossification during long bone development and natural fracture healing initiates by mesenchymal cell condensation, directed by local morphogen signals and mechanical cues. Here, we aimed to mimic development for regeneration of large bone defects. We hypothesized that engineered human m...
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| Veröffentlicht in: | Sci Adv |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Association for the Advancement of Science
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6713501/ https://ncbi.nlm.nih.gov/pubmed/31489377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax2476 |
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