Combinatorial morphogenetic and mechanical cues to mimic bone development for defect repair

Endochondral ossification during long bone development and natural fracture healing initiates by mesenchymal cell condensation, directed by local morphogen signals and mechanical cues. Here, we aimed to mimic development for regeneration of large bone defects. We hypothesized that engineered human m...

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Udgivet i:Sci Adv
Main Authors: Herberg, S., McDermott, A. M., Dang, P. N., Alt, D. S., Tang, R., Dawahare, J. H., Varghai, D., Shin, J.-Y., McMillan, A., Dikina, A. D., He, F., Lee, Y. B., Cheng, Y., Umemori, K., Wong, P. C., Park, H., Boerckel, J. D., Alsberg, E.
Format: Artigo
Sprog:Inglês
Udgivet: American Association for the Advancement of Science 2019
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6713501/
https://ncbi.nlm.nih.gov/pubmed/31489377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax2476
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