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Template-Guided Protein Structure Prediction and Refinement Using Optimized Folding Landscape Force Fields

When good structural templates can be identified, template-based modeling is the most reliable way to predict the tertiary structure of proteins. In this study, we combine template-based modeling with a realistic coarse-grained force field, AWSEM, that has been optimized using the principles of ener...

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Détails bibliographiques
Publié dans:J Chem Theory Comput
Auteurs principaux: Chen, Mingchen, Lin, Xingcheng, Lu, Wei, Schafer, Nicholas P., Onuchic, José N., Wolynes, Peter G.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6713208/
https://ncbi.nlm.nih.gov/pubmed/30240202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.8b00683
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