Human embryonic stem cells display a pronounced sensitivity to the cyclin dependent kinase inhibitor Roscovitine

BACKGROUND: The essentially unlimited expansion potential and the pluripotency of human embryonic stem cells (hESCs) make them attractive for cell-based therapeutic purposes. Although hESCs can indefinitely proliferate in culture, unlike transformed cancer cells, they are endowed with a cell-intrins...

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Gepubliceerd in:BMC Mol Cell Biol
Hoofdauteurs: Videla-Richardson, Guillermo A., Furmento, Verónica A., Garcia, Carolina P., Morris-Hanon, Olivia, Sevlever, Gustavo E., Romorini, Leonardo, Scassa, María E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2019
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6712821/
https://ncbi.nlm.nih.gov/pubmed/31462218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-019-0222-3
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