Frequent retrotransposition of endogenous genes in ERCC2-deficient cells derived from a patient with xeroderma pigmentosum

BACKGROUND: Retrotransposition of protein-coding genes is thought to occur due to the existence of numerous processed pseudogenes in both animals and plants. Unlike retrotransposons including Alu and LINE-1, direct evidence of such retrotransposition events has not been reported to date. Even if suc...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Aoto, Saki, Katagiri, Saki, Wang, Yi, Pagnamenta, Alistair T., Sakamoto-Abutani, Rie, Toyoda, Masashi, Umezawa, Akihiro, Okamura, Kohji
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6712803/
https://ncbi.nlm.nih.gov/pubmed/31455402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1381-z
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