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Oxygen Uptake Rate Soft-Sensing via Dynamic k(L)a Computation: Cell Volume and Metabolic Transition Prediction in Mammalian Bioprocesses
In aerobic cell cultivation processes, dissolved oxygen is a key process parameter, and an optimal oxygen supply has to be ensured for proper process performance. To achieve optimal growth and/or product formation, the rate of oxygen transfer has to be in right balance with the consumption by cells....
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| Udgivet i: | Front Bioeng Biotechnol |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6712683/ https://ncbi.nlm.nih.gov/pubmed/31497597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00195 |
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