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Multiple functional variants in the IL1RL1 region are pretransplant markers for risk of GVHD and infection deaths
Graft-versus-host disease (GVHD) and infections are the 2 main causes of death without relapse after allogeneic hematopoietic cell transplantation (HCT). Elevated soluble serum simulation-2 (sST2), the product of IL1RL1 in plasma/serum post-HCT, is a validated GVHD biomarker. Hundreds of SNPs at 2q1...
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| Publicat a: | Blood Adv |
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| Autors principals: | , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Hematology
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6712530/ https://ncbi.nlm.nih.gov/pubmed/31455667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000075 |
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