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ISG15 Deficiency Enhances HIV-1 Infection by Accumulating Misfolded p53
Macrophages and dendritic cells dominate early immune responses to lentiviruses. HIV-1 sensing by pathogen recognition receptors induces signaling cascades that culminate in type I alpha/beta interferon (IFN-α/β) induction. IFN-α/β signals back via the IFN-α/β receptors, inducing a plethora of IFN-s...
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| Publicado no: | mBio |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6712392/ https://ncbi.nlm.nih.gov/pubmed/31455647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01342-19 |
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