Functional roles of ST8SIA3-mediated sialylation of striatal dopamine D(2) and adenosine A(2A) receptors

Sialic acids are typically added to the end of glycoconjugates by sialyltransferases. Among the six ST8 α-N-acetyl-neuraminide α-2,8-sialyltransferases (ST8SIA) existing in adult brains, ST8SIA2 is a schizophrenia-associated gene. However, the in vivo substrates and physiological functions of most s...

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Pubblicato in:Transl Psychiatry
Autori principali: Lin, Chien-Yu, Lai, Hsing-Lin, Chen, Hui-Mei, Siew, Jian-Jing, Hsiao, Cheng-Te, Chang, Hua-Chien, Liao, Kuo-Shiang, Tsai, Shih-Chieh, Wu, Chung-Yi, Kitajima, Ken, Sato, Chihiro, Khoo, Kay-Hooi, Chern, Yijuang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6712005/
https://ncbi.nlm.nih.gov/pubmed/31455764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-019-0529-z
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