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Priming mobilization of hair follicle stem cells triggers permanent loss of regeneration after alkylating chemotherapy
The maintenance of genetic integrity is critical for stem cells to ensure homeostasis and regeneration. Little is known about how adult stem cells respond to irreversible DNA damage, resulting in loss of regeneration in humans. Here, we establish a permanent regeneration loss model using cycling hum...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6711970/ https://ncbi.nlm.nih.gov/pubmed/31455775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11665-0 |
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