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The Electronic Structure of the Metal Active Site Determines the Geometric Structure and Function of the Metalloregulator NikR
NikR is a nickel-responsive metalloregulator protein that controls the level of Ni(2+) ions in living cells. Previous studies have shown that NikR can bind a series of first row transition metal ions, but only binds to DNA with high affinity as a Ni(2+) complex. To understand this metal selectivity,...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6711802/ https://ncbi.nlm.nih.gov/pubmed/31339709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00542 |
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