A recommended and verified procedure for in situ tryptic digestion of formalin-fixed paraffin-embedded tissues for analysis by matrix-assisted laser desorption/ionization imaging mass spectrometry

Matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS) is a molecular imaging technology uniquely capable of untargeted measurement of proteins, lipids, and metabolites while retaining spatial information about their location in situ. This powerful combination of capabilit...

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Publicado en:J Mass Spectrom
Main Authors: Judd, Audra M., Gutierrez, Danielle B., Moore, Jessica L., Patterson, Nathan Heath, Yang, Junhai, Romer, Carrie E., Norris, Jeremy L., Caprioli, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6711785/
https://ncbi.nlm.nih.gov/pubmed/31254303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jms.4384
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