Human germinal center B cells differ from naïve and memory B cells in CD40 expression and CD40L-induced signaling response

CD40 expression is required for germinal center (GC) formation and function, but the kinetics and magnitude of signaling following CD40 engagement remain poorly characterized in human B cells undergoing germinal center reactions. Here, differences in CD40 expression and signaling responses were comp...

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Publicado no:Cytometry A
Main Authors: Huse, Kanutte, Wogsland, Cara E., Polikowsky, Hannah G., Diggins, Kirsten E., Smeland, Erlend B., Myklebust, June H., Irish, Jonathan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6711772/
https://ncbi.nlm.nih.gov/pubmed/30838773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.a.23737
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