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Pressure-driven release of viral genome into a host nucleus is a mechanism leading to herpes infection

Many viruses previously have been shown to have pressurized genomes inside their viral protein shell, termed the capsid. This pressure results from the tight confinement of negatively charged viral nucleic acids inside the capsid. However, the relevance of capsid pressure to viral infection has not...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Brandariz-Nuñez, Alberto, Liu, Ting, Du, Te, Evilevitch, Alex
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6711703/
https://ncbi.nlm.nih.gov/pubmed/31393262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.47212
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