Phosphodiesterase 10A IgG: A novel biomarker of paraneoplastic neurologic autoimmunity

OBJECTIVE: To describe a novel antibody biomarker of neurologic paraneoplastic autoimmunity specific for phosphodiesterase 10A (PDE10A), a striatum-enriched phosphodiesterase, and to characterize the clinical phenotype of patients with PDE10A immunoglobulin G (IgG). METHODS: We describe 7 patients w...

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Bibliographic Details
Published in:Neurology
Main Authors: Zekeridou, Anastasia, Kryzer, Thomas, Guo, Yong, Hassan, Anhar, Lennon, Vanda, Lucchinetti, Claudia F., Pittock, Sean, McKeon, Andrew
Format: Artigo
Language:Inglês
Published: Lippincott Williams & Wilkins 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6711657/
https://ncbi.nlm.nih.gov/pubmed/31315972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000007971
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