Scalable, semi-automated fluorescence reduction neutralization assay for qualitative assessment of Ebola virus-neutralizing antibodies in human clinical samples

Antibody titers against a viral pathogen are typically measured using an antigen binding assay, such as an enzyme-linked immunosorbent assay (ELISA), which only measures the ability of antibodies to identify a viral antigen of interest. Neutralization assays measure the presence of virus-neutralizin...

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Udgivet i:PLoS One
Main Authors: Postnikova, Elena N., Pettitt, James, Van Ryn, Collin J., Holbrook, Michael R., Bollinger, Laura, Yú, Shuǐqìng, Caì, Yíngyún, Liang, Janie, Sneller, Michael C., Jahrling, Peter B., Hensley, Lisa E., Kuhn, Jens H., Fallah, Mosoka P., Bennett, Richard S., Reilly, Cavan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6711594/
https://ncbi.nlm.nih.gov/pubmed/31454374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0221407
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