SPIONs enhances IL-10-producing macrophages to relieve sepsis via Cav1-Notch1/HES1-mediated autophagy

BACKGROUND: Sepsis is a life-threatening condition caused by dysregulated host responses to infection. Macrophages, which recognize microbial infections through identification of bacterial markers such as lipopolysaccharide (LPS), are crucial to the pathogenesis of sepsis-associated liver injury. Ho...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Xu, Yujun, Li, Yi, Liu, Xinghan, Pan, Yuchen, Sun, Zhiheng, Xue, Yaxian, Wang, Tingting, Dou, Huan, Hou, Yayi
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6711564/
https://ncbi.nlm.nih.gov/pubmed/31692534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S215055
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