Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level

BACKGROUND: In many patients with mild, persistent asthma, the percentage of eosinophils in sputum is less than 2% (low eosinophil level). The appropriate treatment for these patients is unknown. METHODS: In this 42-week, double-blind, crossover trial, we assigned 295 patients who were at least 12 y...

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Udgivet i:N Engl J Med
Main Authors: Lazarus, S.C., Krishnan, J.A., King, T.S., Lang, J.E., Blake, K.V., Covar, R., Lugogo, N., Wenzel, S., Chinchilli, V.M., Mauger, D.T., Dyer, A.-M., Boushey, H.A., Fahy, J.V., Woodruff, P.G., Bacharier, L.B., Cabana, M.D., Cardet, J.C., Castro, M., Chmiel, J., Denlinger, L., DiMango, E., Fitzpatrick, A.M., Gentile, D., Hastie, A., Holguin, F., Israel, E., Jackson, D., Kraft, M., LaForce, C., Lemanske, R.F., Martinez, F.D., Moore, W., Morgan, W.J., Moy, J.N., Myers, R., Peters, S.P., Phipatanakul, W., Pongracic, J.A., Que, L., Ross, K., Smith, L., Szefler, S.J., Wechsler, M.E., Sorkness, C.A.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6711475/
https://ncbi.nlm.nih.gov/pubmed/31112384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1814917
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