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Pharmacokinetics, pharmacodynamics and PKPD modeling of curcumin in regulating antioxidant and epigenetic gene expression in human healthy volunteers

Curcumin is a major component of the spice, turmeric (Curcuma longa) often used in food or as a dietary supplement. Many preclinical studies on curcumin suggest health benefit in many diseases due to its antioxidant/anti-inflammatory and epigenetic effects. The few human studies and curcumin’s unfav...

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Detalhes bibliográficos
Publicado no:Mol Pharm
Main Authors: Cheng, David, Li, Wenji, Wang, Lujing, Lin, Tiffany, Poiani, George, Wassef, Andrew, Hudlikar, Rasika, Ondar, Patricia, Brunetti, Luigi, Kong, Ah-Ng
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6710832/
https://ncbi.nlm.nih.gov/pubmed/30860383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.8b01246
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