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Hypoxia-Inducible Factors as an Alternative Source of Treatment Strategy for Cancer
Hypoxia-inducible factors (HIFs) are transcription factors that activate the transcription of genes necessary to circumvent to hypoxic (low oxygen level) environments. In carcinogenesis, HIFs play a critical role. Indeed, HIF-1α has been validated as a promising target for novel cancer therapeutics,...
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| 發表在: | Oxid Med Cell Longev |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Hindawi
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6710762/ https://ncbi.nlm.nih.gov/pubmed/31485300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/8547846 |
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