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A new era for migraine: Pharmacokinetic and pharmacodynamic insights into monoclonal antibodies with a focus on galcanezumab, an anti-CGRP antibody

PURPOSE: To review pharmacokinetic and pharmacodynamic characteristics of antibodies that bind to soluble ligands within the framework of calcitonin gene-related peptide antibodies. OVERVIEW: Calcitonin gene-related peptide has been implicated in the pathophysiology of migraine. Galcanezumab is an a...

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Détails bibliographiques
Publié dans:Cephalalgia
Auteurs principaux: Kielbasa, William, Helton, Danielle L
Format: Artigo
Langue:Inglês
Publié: SAGE Publications 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6710614/
https://ncbi.nlm.nih.gov/pubmed/30917684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0333102419840780
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