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Pharmacokinetics, exposure, efficacy and safety of obinutuzumab in rituximab‐refractory follicular lymphoma patients in the GADOLIN phase III study

AIMS: Rituximab is standard care in a number of lymphoma subtypes, including follicular lymphoma (FL), although many patients are resistant to rituximab, or develop resistance with repeated treatment, and a high proportion relapse. Obinutuzumab is a novel anti‐CD20 monoclonal antibody with improved...

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Библиографические подробности
Опубликовано в: :Br J Clin Pharmacol
Главные авторы: Gibiansky, Ekaterina, Gibiansky, Leonid, Buchheit, Vincent, Frey, Nicolas, Brewster, Michael, Fingerle‐Rowson, Günter, Jamois, Candice
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6710522/
https://ncbi.nlm.nih.gov/pubmed/31050355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13974
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