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Therapeutic concentration achievement and allograft survival comparing usage of conventional tacrolimus doses and CYP3A5 genotype‐guided doses in renal transplantation patients

AIMS: Although cytochromeP450(CYP)3A5 gene polymorphism affects personalized tacrolimus doses, there is no consensus as to whether CYP3A5 genotypes should be determined to adjust the doses. The aims were to compare the therapeutic ranges and clinical outcomes between the conventional and genotype‐gu...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Anutrakulchai, Sirirat, Pongskul, Cholatip, Kritmetapak, Kittrawee, Limwattananon, Chulaporn, Vannaprasaht, Suda
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6710516/
https://ncbi.nlm.nih.gov/pubmed/31077425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13980
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