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Optimizing the dose in patients treated with imatinib as first line treatment for gastrointestinal stromal tumours: A cost‐effectiveness study

AIMS: Patients with metastatic gastrointestinal stromal tumours (GIST) are treated in first line with the oral tyrosine kinase inhibitor, imatinib, until progressive disease. With this fixed dosing regimen, only approximately 40% of patients reach adequate plasma levels within the therapeutic index....

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Bibliografske podrobnosti
izdano v:Br J Clin Pharmacol
Main Authors: Zuidema, Sander, Desar, Ingrid M.E., van Erp, Nielka P., Kievit, Wietske
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6710511/
https://ncbi.nlm.nih.gov/pubmed/31112617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13990
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