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Profile of tezacaftor/ivacaftor combination and its potential in the treatment of cystic fibrosis

Cystic fibrosis (CF) is a life-limiting autosomal recessive disease caused by dysfunction of the cystic fibrosis transmembrane conductance regulator (CFTR) ion channel. Management of CF has traditionally relied upon managing complications of CFTR protein dysfunction and this has led to a steady impr...

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Detalles Bibliográficos
Publicado en:Ther Clin Risk Manag
Main Authors: Shiferaw, Dejene, Faruqi, Shoaib
Formato: Artigo
Idioma:Inglês
Publicado: Dove 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6710479/
https://ncbi.nlm.nih.gov/pubmed/31692517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TCRM.S165027
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