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Profile of tezacaftor/ivacaftor combination and its potential in the treatment of cystic fibrosis

Cystic fibrosis (CF) is a life-limiting autosomal recessive disease caused by dysfunction of the cystic fibrosis transmembrane conductance regulator (CFTR) ion channel. Management of CF has traditionally relied upon managing complications of CFTR protein dysfunction and this has led to a steady impr...

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Detalhes bibliográficos
Publicado no:Ther Clin Risk Manag
Main Authors: Shiferaw, Dejene, Faruqi, Shoaib
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6710479/
https://ncbi.nlm.nih.gov/pubmed/31692517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TCRM.S165027
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