A conserved regulatory program initiates lateral plate mesoderm emergence across chordates

Cardiovascular lineages develop together with kidney, smooth muscle, and limb connective tissue progenitors from the lateral plate mesoderm (LPM). How the LPM initially emerges and how its downstream fates are molecularly interconnected remain unknown. Here, we isolate a pan-LPM enhancer in the zebr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Prummel, Karin D., Hess, Christopher, Nieuwenhuize, Susan, Parker, Hugo J., Rogers, Katherine W., Kozmikova, Iryna, Racioppi, Claudia, Brombacher, Eline C., Czarkwiani, Anna, Knapp, Dunja, Burger, Sibylle, Chiavacci, Elena, Shah, Gopi, Burger, Alexa, Huisken, Jan, Yun, Maximina H., Christiaen, Lionel, Kozmik, Zbynek, Müller, Patrick, Bronner, Marianne, Krumlauf, Robb, Mosimann, Christian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6710290/
https://ncbi.nlm.nih.gov/pubmed/31451684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11561-7
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