A conserved regulatory program initiates lateral plate mesoderm emergence across chordates

Cardiovascular lineages develop together with kidney, smooth muscle, and limb connective tissue progenitors from the lateral plate mesoderm (LPM). How the LPM initially emerges and how its downstream fates are molecularly interconnected remain unknown. Here, we isolate a pan-LPM enhancer in the zebr...

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Publicat a:Nat Commun
Autors principals: Prummel, Karin D., Hess, Christopher, Nieuwenhuize, Susan, Parker, Hugo J., Rogers, Katherine W., Kozmikova, Iryna, Racioppi, Claudia, Brombacher, Eline C., Czarkwiani, Anna, Knapp, Dunja, Burger, Sibylle, Chiavacci, Elena, Shah, Gopi, Burger, Alexa, Huisken, Jan, Yun, Maximina H., Christiaen, Lionel, Kozmik, Zbynek, Müller, Patrick, Bronner, Marianne, Krumlauf, Robb, Mosimann, Christian
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6710290/
https://ncbi.nlm.nih.gov/pubmed/31451684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11561-7
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