Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program

Chronic kidney disease (CKD), defined by low estimated glomerular filtration rate (eGFR), contributes to global morbidity and mortality. Here we conduct a transethnic Genome-Wide Association Study of eGFR in 280,722 participants of the Million Veteran Program (MVP), with replication in 765,289 parti...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Hellwege, Jacklyn N., Velez Edwards, Digna R., Giri, Ayush, Qiu, Chengxiang, Park, Jihwan, Torstenson, Eric S., Keaton, Jacob M., Wilson, O. D., Robinson-Cohen, Cassianne, Chung, Cecilia P., Roumie, Christianne L., Klarin, Derek, Damrauer, Scott M., DuVall, Scott L., Siew, Edward, Akwo, Elvis A., Wuttke, Matthias, Gorski, Mathias, Li, Man, Li, Yong, Gaziano, J. Michael, Wilson, Peter W. F., Tsao, Philip S., O’Donnell, Christopher J., Kovesdy, Csaba P., Pattaro, Cristian, Köttgen, Anna, Susztak, Katalin, Edwards, Todd L., Hung, Adriana M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6710266/
https://ncbi.nlm.nih.gov/pubmed/31451708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11704-w
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