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Inflammasome inhibition blocks cardiac glycoside cell toxicity

Chronic heart failure and cardiac arrhythmias have high morbidity and mortality, and drugs for the prevention and management of these diseases are a large part of the pharmaceutical market. Among these drugs are plant-derived cardiac glycosides, which have been used by various cultures over millenni...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: LaRock, Doris L., Sands, Jenna S., Ettouati, Ethan, Richard, Marine, Bushway, Paul J., Adler, Eric D., Nizet, Victor, LaRock, Christopher N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6709640/
https://ncbi.nlm.nih.gov/pubmed/31300552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008330
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