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Metabolic engineering of roseoflavin-overproducing microorganisms

BACKGROUND: Roseoflavin, a promising broad-spectrum antibiotic, is naturally produced by the bacteria Streptomyces davaonensis and Streptomyces cinnabarinus. The key enzymes responsible for roseoflavin biosynthesis and the corresponding genes were recently identified. In this study we aimed to enhan...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Mora-Lugo, Rodrigo, Stegmüller, Julian, Mack, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6709556/
https://ncbi.nlm.nih.gov/pubmed/31451111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-019-1181-2
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