7-Ketocholesterol and cholestane-triol increase expression of SMO and LXRα signaling pathways in a human breast cancer cell line

Oxysterols are 27-carbon oxidation products of cholesterol metabolism. Oxysterols possess several biological actions, including the promotion of cell death. Here, we examined the ability of 7-ketocholesterol (7-KC), cholestane-3β-5α-6β-triol (triol), and a mixture of 5α-cholestane-3β,6β-diol and 5α-...

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Détails bibliographiques
Publié dans:Biochem Biophys Rep
Auteurs principaux: Levy, Debora, de Melo, Thatiana Correa, Oliveira, Beatriz A., Paz, Jessica L., de Freitas, Fabio A., Reichert, Cadiele O., Rodrigues, Alessandro, Bydlowski, Sergio P.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6709374/
https://ncbi.nlm.nih.gov/pubmed/31463370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2018.12.008
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