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Coxsackievirus Type B3 Is a Potent Oncolytic Virus against KRAS-Mutant Lung Adenocarcinoma

KRAS mutant (KRAS(mut)) lung adenocarcinoma is a refractory cancer without available targeted therapy. The current study explored the possibility to develop coxsackievirus type B3 (CVB3) as an oncolytic agent for the treatment of KRAS(mut) lung adenocarcinoma. In cultured cells, we discovered that C...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Ther Oncolytics
Hauptverfasser: Deng, Haoyu, Liu, Huitao, de Silva, Tanya, Xue, YuanChao, Mohamud, Yasir, Ng, Chen Seng, Qu, Junyan, Zhang, Jingchun, Jia, William W.G., Lockwood, William W., Luo, Honglin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Gene & Cell Therapy 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6709373/
https://ncbi.nlm.nih.gov/pubmed/31463367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2019.07.003
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