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A novel mutation in SPTA1 identified by whole exome sequencing in a Chinese family for hereditary elliptocytosis presenting with hyperbilirubinemia: A case report

RATIONALE: Hereditary elliptocytosis is an inherited disorder characterized by the elliptical red blood cells (RBCs) on the peripheral blood smear and related hemolysis, mainly results from a heterozygous mutation in the genes that encode protein 4.1, α-spectrin, β-spectrin. Mutations of SPTA1 are t...

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Vydáno v:Medicine (Baltimore)
Hlavní autoři: Xi, Yaming, Wang, Lina, Zhang, Pengpeng, Jia, Mingfeng, Li, Zijian
Médium: Artigo
Jazyk:Inglês
Vydáno: Wolters Kluwer Health 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708995/
https://ncbi.nlm.nih.gov/pubmed/31145309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000015800
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