Efficient Front-Rear Coupling in Neutrophil Chemotaxis by Dynamic Myosin II Localization

Efficient chemotaxis requires rapid coordination between different parts of the cell in response to changing directional cues. Here we investigate the mechanism of front-rear coordination in chemotactic neutrophils. We find that changes in the protrusion rate at the cell front are instantaneously co...

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Publicat a:Dev Cell
Autors principals: Tsai, Tony Y.-C., Collins, Sean R., Chan, Caleb K., Hadjitheodorou, Amalia, Lam, Pui-ying, Lou, Sunny S., Yang, Hee Won, Jorgensen, Julianne, Ellett, Felix, Irimia, Daniel, Davidson, Michael W., Fischer, Robert S., Huttenlocher, Anna, Meyer, Tobias, Ferrell, James E., Theriot, Julie A.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708378/
https://ncbi.nlm.nih.gov/pubmed/31014479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.03.025
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