Highly diversified shrew hepatitis B viruses corroborate ancient origins and divergent infection patterns of mammalian hepadnaviruses

Shrews, insectivorous small mammals, pertain to an ancient mammalian order. We screened 693 European and African shrews for hepatitis B virus (HBV) homologs to elucidate the enigmatic genealogy of HBV. Shrews host HBVs at low prevalence (2.5%) across a broad geographic and host range. The phylogenet...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Rasche, Andrea, Lehmann, Felix, König, Alexander, Goldmann, Nora, Corman, Victor M., Moreira-Soto, Andres, Geipel, Andreas, van Riel, Debby, Vakulenko, Yulia A., Sander, Anna-Lena, Niekamp, Hauke, Kepper, Ramona, Schlegel, Mathias, Akoua-Koffi, Chantal, Souza, Breno F. C. D., Sahr, Foday, Olayemi, Ayodeji, Schulze, Vanessa, Petraityte-Burneikiene, Rasa, Kazaks, Andris, Lowjaga, Kira A. A. T., Geyer, Joachim, Kuiken, Thijs, Drosten, Christian, Lukashev, Alexander N., Fichet-Calvet, Elisabeth, Ulrich, Rainer G., Glebe, Dieter, Drexler, Jan Felix
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2019
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708359/
https://ncbi.nlm.nih.gov/pubmed/31371507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1908072116
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