TNFR2 promotes Treg-mediated recovery from neuropathic pain across sexes

Tumor necrosis factor receptor 2 (TNFR2) is a transmembrane receptor that is linked to immune modulation and tissue regeneration. Here, we show that TNFR2 essentially promotes long-term pain resolution independently of sex. Genetic deletion of TNFR2 resulted in impaired neuronal regeneration and chr...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Fischer, Roman, Sendetski, Maksim, del Rivero, Tania, Martinez, George F., Bracchi-Ricard, Valerie, Swanson, Kathryn A., Pruzinsky, Elizabeth K., Delguercio, Niky, Rosalino, Michael J., Padutsch, Tanja, Kontermann, Roland E., Pfizenmaier, Klaus, Bethea, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708347/
https://ncbi.nlm.nih.gov/pubmed/31391309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1902091116
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