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Liquid-crystalline phase transitions in lipid droplets are related to cellular states and specific organelle association

Lipid droplets (LDs) are ubiquitous organelles comprising a central hub for cellular lipid metabolism and trafficking. This role is tightly associated with their interactions with several cellular organelles. Here, we provide a systematic and quantitative structural description of LDs in their nativ...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Mahamid, Julia, Tegunov, Dimitry, Maiser, Andreas, Arnold, Jan, Leonhardt, Heinrich, Plitzko, Jürgen M., Baumeister, Wolfgang
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708344/
https://ncbi.nlm.nih.gov/pubmed/31375636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1903642116
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