Melanin-dot–mediated delivery of metallacycle for NIR-II/photoacoustic dual-modal imaging-guided chemo-photothermal synergistic therapy

Discrete Pt(II) metallacycles have potential applications in biomedicine. Herein, we engineered a dual-modal imaging and chemo-photothermal therapeutic nano-agent 1 that incorporates discrete Pt(II) metallacycle 2 and fluorescent dye 3 (emission wavelength in the second near-infrared channel [NIR-II...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sun, Yue, Ding, Feng, Chen, Zhao, Zhang, Ruiping, Li, Chonglu, Xu, Yuling, Zhang, Yi, Ni, Ruidong, Li, Xiaopeng, Yang, Guangfu, Sun, Yao, Stang, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Physical Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708342/
https://ncbi.nlm.nih.gov/pubmed/31391305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1908761116
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