Endocytosis of commensal antigens by intestinal epithelial cells regulates mucosal T cell homeostasis

INTRODUCTION: Although commensal microbes populate our barrier surfaces without causing obvious disease, they nonetheless modulate host physiology and immunity. Commensal bacteria can regulate host T cell differentiation and function and a large fraction of mucosal tissue-resident T cells are though...

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Publicado no:Science
Main Authors: Ladinsky, Mark S., Araujo, Leandro P., Zhang, Xiao, Veltri, John, Galan-Diez, Marta, Soualhi, Salima, Lee, Carolyn, Irie, Koichiro, Pinker, Elisha Y., Narushima, Seiko, Bandyopadhyay, Sheila, Nagayama, Manabu, Elhenawy, Wael, Coombes, Brian K., Ferraris, Ronaldo P., Honda, Kenya, Iliev, Iliyan D., Gao, Nan, Bjorkman, Pamela J., Ivanov, Ivaylo I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708280/
https://ncbi.nlm.nih.gov/pubmed/30846568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aat4042
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