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Contribution of Oxidative Stress and Impaired Biogenesis of Pancreatic β-Cells to Type 2 Diabetes

Significance: Type 2 diabetes development involves multiple changes in β-cells, related to the oxidative stress and impaired redox signaling, beginning frequently by sustained overfeeding due to the resulting lipotoxicity and glucotoxicity. Uncovering relationships among the dysregulated metabolism,...

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Bibliografiska uppgifter
I publikationen:Antioxid Redox Signal
Huvudupphovsmän: Ježek, Petr, Jabůrek, Martin, Plecitá-Hlavatá, Lydie
Materialtyp: Artigo
Språk:Inglês
Publicerad: Mary Ann Liebert, Inc., publishers 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708273/
https://ncbi.nlm.nih.gov/pubmed/30450940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2018.7656
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