Neoantigen vaccine: an emerging tumor immunotherapy

Genetic instability of tumor cells often leads to the occurrence of a large number of mutations, and expression of non-synonymous mutations can produce tumor-specific antigens called neoantigens. Neoantigens are highly immunogenic as they are not expressed in normal tissues. They can activate CD4+ a...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Mol Cancer
Autori principali: Peng, Miao, Mo, Yongzhen, Wang, Yian, Wu, Pan, Zhang, Yijie, Xiong, Fang, Guo, Can, Wu, Xu, Li, Yong, Li, Xiaoling, Li, Guiyuan, Xiong, Wei, Zeng, Zhaoyang
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708248/
https://ncbi.nlm.nih.gov/pubmed/31443694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-019-1055-6
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