LncRNA AFAP1-AS1 promotes tumorigenesis and epithelial-mesenchymal transition of osteosarcoma through RhoC/ROCK1/p38MAPK/Twist1 signaling pathway

BACKGROUND: An increasing number of studies have demonstrated that long non-coding RNAs (lncRNAs) play pivotal roles in cancer onset and development. LncRNA AFAP1-AS1 has been validated to be abnormally upregulated and play oncogenic roles in various malignant tumors. The biological role and mechani...

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Vydáno v:J Exp Clin Cancer Res
Hlavní autoři: Shi, Deyao, Wu, Fashuai, Mu, Shidai, Hu, Binwu, Zhong, Binlong, Gao, Feng, Qing, Xiangcheng, Liu, Jianxiang, Zhang, Zhicai, Shao, Zengwu
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708246/
https://ncbi.nlm.nih.gov/pubmed/31443665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1363-0
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